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Há 2 dias · Microsatellite instability (MSI) is found in ∼5% of all patients with metastatic colorectal cancer (mCRC). Solid evidence has shown that MSI-high/mismatch repair deficient (MSI-H/dMMR) tumors are less responsive to chemotherapy and sensitive to immunotherapy due to a higher tumor neoantigen load and immune cell infiltration.1,2
22 de mai. de 2024 · Pan-Asian adapted ESMO consensus guidelines for the management of patients with metastatic colorectal cancer: a JSMO–ESMO initiative endorsed by CSCO, KACO, MOS, SSO and TOS
22 de mai. de 2024 · Clinical Practice Guideline – Metastatic Colorectal Cancer. ESMO is Europe’s leading medical oncology society, providing a professional network for its members and working with national societies across Europe.
27 de mai. de 2024 · As for 2020 recommendations, ESMO recommends running tumour NGS in advanced non-squamous non-small-cell lung cancer, prostate cancer, colorectal cancer, cholangiocarcinoma, and ovarian cancer. Moreover, it is recommended to carry out tumour NGS in clinical research centres and under specific circumstances discussed with patients.
15 de mai. de 2024 · Neoadjuvant therapy has an established role in the treatment of patients with colorectal cancer. However, its role continues to evolve due to both advances in the available treatment modalities, and refinements in the indications for neoadjuvant treatment and subsequent surgery. Methods.
22 de mai. de 2024 · This ESMO Clinical Practice Guideline provides key recommendations for managing renal cell carcinoma. The guideline covers imaging and diagnosis, staging and risk assessment, treatment and follow-up. Algorithms for the management of localised and advanced or metastatic disease are provided.
28 de mai. de 2024 · In this commentary, we review surveillance imaging recommendations after curative-intent treatment from international, regional, and country-specific guidelines (including ASCO, European Society of Medical Oncology [ESMO], National Comprehensive Cancer Network [NCCN], Cancer Care Ontario [CCO], and National Cancer Grid of India [NCGI]).
