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25 de mai. de 2024 · A prion / ˈ p r iː ɒ n / ⓘ is a misfolded protein that can induce misfolding of normal variants of the same protein and trigger cellular death. Prions cause prion diseases known as transmissible spongiform encephalopathies (TSEs) that are transmissible, fatal neurodegenerative diseases in humans and animals.
Há 4 dias · Lockheed WP-3D Orion. Developed into. Lockheed P-7. The Lockheed P-3 Orion is a four-engined, turboprop anti-submarine and maritime surveillance aircraft developed for the United States Navy and introduced in the 1960s.
24 de mai. de 2024 · Stanley B. Prusiner (born May 28, 1942, Des Moines, Iowa, U.S.) is an American biochemist and neurologist whose discovery in 1982 of disease-causing proteins called prions won him the 1997 Nobel Prize for Physiology or Medicine.
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Há 5 dias · Metrics. Abstract. Oligodendrocyte-lineage cells, including NG2 glia, undergo prominent changes in various neurodegenerative disorders. Here, we identify a neuroprotective role for NG2 glia against...
Há 5 dias · Background Prion diseases are transmissible and fatal neurodegenerative diseases characterized by accumulation of misfolded prion protein isoform (PrPSc), astrocytosis, microgliosis, spongiosis, and neurodegeneration. Elevated levels of cell membrane associated PrPSc protein and inflammatory cytokines hint towards the activation of death receptor (DR) pathway/s in prion diseases. Activation of ...
Há 3 dias · A zoonosis (/ z oʊ ˈ ɒ n ə s ɪ s, ˌ z oʊ ə ˈ n oʊ s ɪ s /; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a bacterium, virus, parasite, or prion) that can jump from a non-human (usually a vertebrate) to a human and vice versa.
17 de mai. de 2024 · Last Updated May 20, 2024. A substantial species barrier prevents chronic wasting disease (CWD), a cervid prion disease with unknown zoonotic potential, from being transmitted to humans, new NIH...
