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13 de jul. de 2015 · Breast cancer remains the leading cause of cancer mortality worldwide, despite a significant decline in death rates due to early detection. The majority of cancer mortalities are due to the metastasis of tumor cells to other organs. Metastasis or tumor cell dissemination occurs via the hematogenous and lymphatic systems.
12 de nov. de 2021 · Cancer metastasis is the process by which primary cancer cells invade through the lymphatic or blood vessels to distant sites. The molecular mechanisms by which cancer cells spread either through the lymphatic versus blood vessels or both are not well established. Two major developments have helped us to understand the process more clearly. First, the development of the sentinel lymph node ...
20 de jan. de 2017 · Colorectal cancer (CRC) is the third most common cancer worldwide, ranking as high as the second leading cause of cancer-related deaths in developed countries.1, 2, 3 The liver is recognized as the most common site of CRC metastasis because the majority of the intestinal mesenteric drainage enters the hepatic portal venous system.
7 de jul. de 2017 · In most patients, lymph node metastasis is not the cause of death but is correlated with spread to vital organs ().The association between lymphatic and distant metastasis has been known for at least 150 years and, together with the observation that lymph node disease often precedes systemic disease, has engendered the view that affected lymph nodes may give rise to distant metastases (10–12).
Metastasis is the leading reason for the resultant mortality of patients with cancer. The past few decades have witnessed remarkable progress in understanding the molecular and cellular basis of this lethal process in cancer. The current article summarizes some of the key progress in this area and discusses the role of cell junctions, cell adhesions, epithelial-mesenchymal transition, angio ...
4 de mar. de 2022 · Colorectal cancer (CRC) is one of the most frequently occurring malignancy tumors with a high morbidity additionally, CRC patients may develop liver metastasis, which is the major cause of death.
12 de nov. de 2021 · Cancer metastasis is the process by which primary cancer cells invade through the lymphatic or blood vessels to distant sites. The molecular mechanisms by which cancer cells spread either through the lymphatic versus blood vessels or both are not well established. Two major developments have helped us to understand the process more clearly.
