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  1. The consensus molecular subtype (CMS) classification of colorectal cancer is based on bulk transcriptomics. The underlying epithelial cell diversity remains unclear. We analyzed 373,058 single-cell transcriptomes from 63 patients, focusing on 49,155 epithelial cells. We identified a pervasive geneti …

  2. 29 de mar. de 2022 · It is an alternative method of image augmentation which extracts simulated images using simple transformations such as rotation, shearing, stretching, etc. In this paper, a systematic review for the application of DL in colorectal cancer, using digital image analysis in histopathological images, is presented.

  3. 29 de mar. de 2022 · Colorectal cancer (CRC), which comprises colon and/or rectum cancer, represents a significant health problem as the world’s third most commonly diagnosed and second most fatal cancer globally [1]. Approximately 9.4% of cancer-related deaths were due to CRC in 2020 [2].

  4. The molecular and clinical characteristics of these gene fusions are not well definedin colorectal cancer patients (CRC). In this study, we aimed to defineclinical and molecular characteristics of fusion genes in patients with CRC who underwent molecular profiling. Methods:Molecular characteristics of tissue confirmed917 CRC patients were ...

  5. Há 2 dias · Correction: Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2. Yuchun Niu, Feng Ma, Weimei Huang, Shun Fang, Man Li, Ting Wei and Linlang Guo. Molecular Cancer 2024 23 :112. Correction Published on: 25 May 2024.

  6. 1 de set. de 2022 · Introduction. Colon cancer (CC) is the third leading cause of cancer-related death in adult patients in the US. An estimated 106,180 new CC cases and 52,580 deaths are expected in 2022. 1 Although new treatments have improved outcomes, 2, 3 the fiveyear relative survival remains poor at only 64.7%. 2 The odds are worse for patients with metastatic disease as their fiveyear survival rate is ...

  7. 30 de abr. de 2022 · CSCO guidelines for colorectal cancer version 2022: Updates and discussions. A large number of patients with a history of cancer or oncology problems were admitted to the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, and the once-in-a-lifetime operation to correct these problems proved to be successful. Expand.