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1 de jan. de 2022 · Abstract. PurposeBrain metastasis (BM) in colorectal cancer patients is rare and is associated with dismal outcomes. Our study aims to evaluate the incidence and predictors of BM in patients with ...
colorectal adenocarcinoma specimens with available paraffin blocks were evaluated by immunohistochemistry. Immunostaining of the primary colorectal tumor was performed in 5 of the 11 patients in whom primary and brain metastases were available, to allow compari-son of staining intensity between the primary and metastatic tumor.
26 de nov. de 2012 · Colorectal cancer is one of the most common digestive tract malignancies in the world. Owing to the newer and more effective systemic therapies, the life of colorectal cancer patients can be remarkably prolonged, and the incidence of brain metastases is increasing. However, little is known about the underlying mechanisms of brain metastasis from colorectal cancer. Here we review the tumor ...
31 de jul. de 2019 · The incidence of brain metastases by origin was reported as follows [ 1, 2 ]; lung cancer – 16 to 20%, melanoma – 7%, renal cell cancer – 7 to 10%, breast cancer – 5%, and colorectal cancer (CRC) – 1 to 2%. Regarding prognostic factors of brain metastases, the Radiation Therapy Oncology Group (RTOG) proposed and validated recursive ...
28 de abr. de 2022 · Compared to liver and lung metastases, brain metastases (BMs) from colorectal cancer (CRC) are rare and remain poorly investigated despite the anticipated rise in their incidence. CRC patients bearing BM have a dismal prognosis with a median survival of 3–6 months, significantly lower than that of patients with BM from other primary tumors, and of those with metastatic CRC manifesting ...
24 de jul. de 2023 · Background The aim of this study was to identify the heterogeneous and homogeneous prognostic factors associated with distant metastasis to the liver, lung, bone, and brain in colorectal cancer (CRC) patients and then construct nomograms to predict the prognosis. Methods CRC patients registered in the surveillance, epidemiology, and end results database between 2010 and 2017 were included. A ...
plasms OR cancer of the colon OR cancer of the rectum OR adenocarcinoma colon OR adenocarcinoma rectum OR adenocarcinoma colorectal OR colonic carcinoma OR rectal carcinoma OR colonic neoplasm OR rectal neoplasm). In EMBASE, the search was conducted by combining subject headings brain metastases/with colorectal adenoma/or colorectal cancer/or ...
