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Há 2 dias · Metastatic colorectal cancer ... The portal vein, which drains blood from the gastrointestinal tract, ... the spread of cancer to regional lymph nodes is associated with diminished DFS 15.
Há 2 dias · Studies show that inflammation induced by cancer is a key factor in carcinogenesis. Here, we sought to assess the relationship between patients with locally advanced rectal cancer (LARC) and the lymphocyte to neutrophil granulocyte ratio (LGR) prior to neoadjuvant chemoradiotherapy (nCRT) and distant metastasis-free survival (DMFS). Using a receiver operating characteristic (ROC) analysis of ...
22 de mai. de 2024 · Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer death worldwide [].In recent years, with the widespread use of cancer screening programs, the introduction of molecularly targeted biological drugs, and the use of surgical and local ablative treatments in metastatic patients, mortality has decreased and survival outcomes have improved [].
8 de mai. de 2024 · Abnormal angiogenesis leads to tumor progression and metastasis in colorectal cancer (CRC). This study aimed to elucidate the association between angiogenesis-related genes, including...
4 de mai. de 2024 · The treatment of metastatic colorectal cancer (mCRC) remains challenging. There has been substantial progress in understanding the molecular pathology of the disease that has led to meaningful advancements in treatment options with varying mechanisms of action, although treatment remains costly.
Há 3 dias · Over the past decade, proximal colon adenocarcinomas have been associated with worse overall and cancer-specific survival compared to distal cancers[1,2]. The explanation for these observations remains unclear. We hypothesized that proximal lesions may present with a more aggressive tumor biology leading to higher rates of lymph node (LN) metastases, and therefore, worse oncologic outcomes.
6 de mai. de 2024 · Li X, Zhang Q, Zhao L, Jiang L, Qi A, Wei Q, Song X, Wang L, Zhang L, Zhao Y, Lv X, Wei M, Zhao L. A combined four-mRNA signature Associated with lymphatic metastasis for prognosis of Colorectal Cancer. J Cancer. 2020;11(8):2139–49. https://doi.org/10.7150/jca.38796. PMID: 32127941; PMCID: PMC7052913.
