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12 de mar. de 2014 · Colorectal cancer is one of the most frequent malignant tumors and a leading cause of cancer-related death. One third of the patients develop a metastasis during the course of the disease. Because of that, it is very important to know about the evolution of the illness, how to make a quick diagnosis and how to provide an appropriate treatment depending on the tumor and the location of the ...
Metastasis is the leading reason for the resultant mortality of patients with cancer. The past few decades have witnessed remarkable progress in understanding the molecular and cellular basis of this lethal process in cancer. The current article summarizes some of the key progress in this area and discusses the role of cell junctions, cell adhesions, epithelial-mesenchymal transition, angio ...
7 de dez. de 2021 · Vascular invasion is a common feature of colorectal cancer and its liver metastases. Intrahepatic portal venous invasion local to resected metastases occurs in approximately a quarter of cases (reported range 10-49%) and hepatic venous invasion in approximately one tenth of cases (reported range 5-24%) ( 10 ).
30 de mar. de 2022 · Metastatic colorectal cancer is an advanced condition where cancer spreads, or metastasizes, to other parts of the body. The most common organ that it spreads to is the liver. Learn more.
7 de jul. de 2017 · In most patients, lymph node metastasis is not the cause of death but is correlated with spread to vital organs ().The association between lymphatic and distant metastasis has been known for at least 150 years and, together with the observation that lymph node disease often precedes systemic disease, has engendered the view that affected lymph nodes may give rise to distant metastases (10–12).
Despite encouraging advances in both local and systemic treatment over the past two decades, cancer remains the leading cause of death worldwide. Metastasis, a process of cancer cells spreading from the primary tumor to surrounding tissues and to distant organs is the primary cause of cancer mortality. It is estimated that metastasis is responsible for ∼90% of cancer deaths [1]. This has not ...
5 de jan. de 2015 · Baumhoer D, Thiesler T, Maurer CA, Huber A, Cathomas G. Impact of using elastic stains for detection of venous invasion in the prognosis of patients with lymph node negative colorectal cancer. Int J Colorectal Dis (2010) 25:741–6. 10.1007/s00384-010-0890-0 [Google Scholar]
