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10 de jan. de 2022 · Our miRNA-based signature could perform well in distinguishing breast cancer cases from non-cancer controls as evidenced by a high AUC of 0.915 achieved in validation phase 2, which comprised...
23 de jun. de 2022 · Haiyan Hu. Scientific Reports 12, Article number: 10618 ( 2022 ) Cite this article. 3603 Accesses. 7 Citations. 3 Altmetric. Metrics. Abstract. Accurate identification of microRNA (miRNA)...
13 de jul. de 2018 · Current tools assume that most of the knowledge defining a microRNA-gene interaction can be captured by analysing the binding produced in the seed region (∼ the first 8nt in the miRNA). However, recent studies show that the whole microRNA can be important and form non-canonical targets.
- Albert Pla, Xiangfu Zhong, Xiangfu Zhong, Simon Rayner, Simon Rayner
- 2018
1 de abr. de 2021 · In this Review, we discuss the three main modes of miRNA:miRNA regulation: direct, indirect and global interactions, and their implications in cancer biology. We also discuss the cell-type-specific nature of miRNA:miRNA interactions, current experimental approaches and bioinformatic techniques, and how these strategies are not ...
- Meredith Hill, Nham Tran, Nham Tran
- 2021
15 de jul. de 2022 · In this work, we propose a novel computational method, named BNEMDI, which predicts miRNA–drug interactions using drug substructure fingerprint, miRNA sequence, and MDIs bipartite graph. We have collected known MDI from three databases (e.g., ncDR, RNAInter, and SM2miR) and split them into five datasets.
17 de jun. de 2021 · A novel miRNA-disease association prediction model using dual random walk with restart and space projection federated method. Ang Li , Yingwei Deng , Yan Tan, Min Chen. Published: June 17, 2021. https://doi.org/10.1371/journal.pone.0252971. Article. Authors. Metrics. Comments. Media Coverage. Reader Comments. Figures. Abstract.
