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  1. 4 de ago. de 2022 · Molecular characterization of colorectal cancer related peritoneal metastatic disease | Nature Communications. Article. Open access. Published: 04 August 2022. Molecular...

  2. 24 de mai. de 2023 · Details. Online-only access $25.00. Details. PDF download and online access $59.00. Details. Check out. Abstract. Tumor profiling and targeted therapy revolutionized the treatment strategies of metastatic colorectal cancer (mCRC) in the last decade.

  3. Coloncancer(CC)isthethirdleadingcauseofcancer-related death inadultpatientsintheUS.Anestimated106,180newCC cases and 52,580 deathsareexpected in2022. Althoughnew 1. 2 , treatments have 3 improved outcomes, thefiveyearrelativesurvival remains pooratonly64.7%. 2 Theoddsareworseforpatientswith.

  4. 22 de jun. de 2022 · CRC involves genetic and epigenetic modifications in colonic epithelium, leading to colon adenocarcinoma. The current review highlights the pathogenic mechanisms and multifactorial etiology of CRC, influenced by apoptosis, inflammation, and autophagy pathways.

  5. 1 de set. de 2022 · Colon cancer (CC) is the third leading cause of cancer-related death in adult patients in the US. An estimated 106,180 new CC cases and 52,580 deaths are expected in 2022. 1 Although new treatments have improved outcomes, 2 , 3 the fiveyear relative survival remains poor at only 64.7%. 2 The odds are worse for patients with ...

  6. 2 de jun. de 2022 · 3535Background: Approximately 20% of colorectal cancer (CRC) has an activating mutation in the PIK3CA oncogene. PIK3CA codes for the catalytic subunit of phosphoinos... Molecular characteristics of advanced colorectal cancer and multi-hit PIK3CA mutations. | Journal of Clinical Oncology

  7. 29 de mar. de 2022 · Colorectal Cancer: A Review of Carcinogenesis, Global Epidemiology, Current Challenges, Risk Factors, Preventive and Treatment Strategies. Cancers 2022, 14, 1732.https:// doi.org/10.3390/cancers14071732 Academic Editors: Luis Bujanda, Ajay Goel and Ane Etxart Received: 14 March 2022 Accepted: 27 March 2022 Published: 29 March 2022