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In the present review, we summarize the approaches to selecting the most suitable lipid (s)-based drug delivery system, including characterization, especially for oral delivery, of both physicochemical and biopharmaceutical aspects and properties of assorted excipients as well as the related patent reports.
- Vikas Pandey, Seema Kohli
- 2018
1 de mai. de 2018 · Request PDF | Lipids and Surfactants: The Inside Story of Lipid-Based Drug Delivery Systems | In the bioavailability enhancement of poorly aqueous soluble drugs,...
13 de jul. de 2021 · Lipid systems are biocompatible, inert and biodegradable, stable and deliver at the target with the desired effect. This paper attempt to describe several types of lipid particles used to...
1 de ago. de 2023 · Lipid based drug delivery systems (LBDDS) are valuable and biocompatible nano-carriers for the vehiculation and potential delivery of various hydrophilic, hydrophobic, or amphiphilic compounds. LBDDS have the advantage of targeted drug delivery, as free drugs may have poor targeting, higher systemic toxicity, and possibilities of drug resistance.
Key Points. Highly potent but poorly water-soluble drug (PWSD) candidates are common outcomes of contemporary drug discovery programmes. These lipophilic compounds often exhibit poor systemic...
- Christopher John Porter, Natalie Trevaskis, William Neil Charman
- 2007
18 de out. de 2022 · Lipid-Based Drug Delivery System (LBDDS): An Emerging Paradigm to Enhance Oral Bioavailability of Poorly Soluble Drugs. Review. Published: 18 October 2022. Volume 1 , pages 648–663, ( 2023 ) Cite this article. Download PDF. Roohi Kesharwani, Pankaj Jaiswal, Dilip Kumar Patel & Pankaj Kumar Yadav. 3449 Accesses. 9 Citations. Explore all metrics.
1 de dez. de 2013 · Lipid-based drug delivery systems play an important role in the delivery of hydrophobic drugs with low bioavailability by using various lipids as carriers. Download : Download full-size image. Key words. Lipid-based formulation. Lipid excipient. Solubilization. Lymphatic absorption. 1. Introduction.
