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  1. Isabella, Princess of Asturias (2 October 1470 – 23 August 1498) was the eldest daughter and heiress presumptive of King Ferdinand II of Aragon and Queen Isabella I of Castile. She was Queen of Portugal as the wife of King Manuel I from 30 September 1497 until her death the following year.

  2. Isabella, Princess of Asturias (2 October 1470 – 23 August 1498) was the eldest daughter and heiress presumptive of King Ferdinand II of Aragon and Queen Isabella I of Castile. She was Queen of Portugal as the wife of King Manuel I from 30 September 1497 until her death the following year.