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Há 22 horas · Mirtazapine is a tetracyclic piperazinoazepine; mianserin was developed by the same team of organic chemists and mirtazapine differs from it via addition of a nitrogen atom in one of the rings. [114] : 429 [115] [116] It is a racemic mixture of enantiomers. The ( S )- (+)-enantiomer is known as esmirtazapine .